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Symbol
Name
ID
Trp53
transformation related protein 53
MGI:98834
Phenotype annotations related to renal/urinary system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased level of L-fucose in urine
Abnormality of the bladder
Nephropathy
Nephrotic syndrome
Acute kidney injury
Renal neoplasm
Nephroblastoma
Renal cell carcinoma
Disease(s) Associated with TP53
colorectal cancer
Li-Fraumeni syndrome
Li-Fraumeni syndrome 1
multiple myeloma
stomach cancer

Mouse Phenotypes
renal/urinary system phenotype
increased urinary system tumor incidence
abnormal kidney development
decreased kidney weight
small kidney
renal hypoplasia
Availability Mouse Genotype
Trp53tm1Ldo/Trp53+
Trp53tm1Tyj/Trp53+
Tg(Trp53A135V)L3Ber/0
Trp53tm1Brn/Trp53tm1Brn
Tg(Upk2-cre)1Rkl/0  (conditional)
*
Tg(CMV-cre)1Cgn/0
Trp53tm4Att/Trp53+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory